Less than 1% of the phenylephrine…
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Less than 1% of the phenylephrine is absorbed into the bloodstream after being swallowed, they estimated. Far higher doses could "be needed to achieve a clinically meaningful outcome which would raise significant questions about safety."
"Furthermore, there are no clinical data demonstrating that oral PE is effective as a nasal decongestant at any dosage," the FDA's scientists wrote. (CBS News | ALEXANDER TIN)